This week’s “First Opinion Podcast” is a special two-part episode focusing on the controversial — some say inflammatory — FDA decision to approve aducanumab, an Alzheimer’s drug developed by Biogen that will be marketed as Aduhelm. In these two episodes, I talk with two Alzheimer’s experts with vastly different viewpoints on the news: Dennis Selkoe, a physician and scientist whose research is at the core of how Aduhelm works; and Jason Karlawish, an Alzheimer’s physician who does not believe the drug is ready to be approved.
Selkoe wrote a First Opinion in 2019 on how research on aducanumab could “open the floodgates” for other, possibly better, Alzheimer’s therapies. The headline of Karlawish’s First Opinion, published a week before the long-awaited FDA decision, succinctly captured his stance: “If the FDA approves Biogen’s Alzheimer’s treatment, I won’t prescribe it.”
For even more coverage of the Biogen news, listen to the latest episode of “The Readout LOUD.”
And if you have any feedback for us — First Opinion authors to feature on the podcast, vocal mannerisms the host needs to jettison, kudos or darts — email us at [email protected] and please put “podcast” in the subject line.